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Using gene therapy to manipulate the immune system in the fight against B cell leukemias

INTRODUCTION: Over 20 years ago, chimeric antigen receptors (CARs) were created to endow T-cells with new antigen-specificity and create a therapy that could eradicate cancer and provide life-long protection against recurrence. Steady progress has led to significant improvements with CAR design and...

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Detalhes bibliográficos
Publicado no:Expert Opin Biol Ther
Main Authors: Bouhassira, Diana CG, Thompson, Joshua J, Davila, Marco L
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586131/
https://ncbi.nlm.nih.gov/pubmed/25666545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2015.1014792
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