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Manipulating Immune Tolerance with Micro-RNA Regulated Gene Therapy

The success of in vivo gene therapy greatly depends on the ability to control the immune response toward the therapeutic transgene. Over the last decade several vector-based and pharmacological approaches have been explored to control the immune-mediated clearance of transgene-expressing cells after...

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Detalhes bibliográficos
Main Authors: Goudy, Kevin Scott, Annoni, Andrea, Naldini, Luigi, Roncarolo, Maria-Grazia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229161/
https://ncbi.nlm.nih.gov/pubmed/22144977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2011.00221
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