Recombinant human endostatin enhances the radioresponse in esophageal squamous cell carcinoma by normalizing tumor vasculature and reducing hypoxia

The aim of this study was to investigate the effect of recombinant human endostatin (rh-Endo) in combination with radiation therapy (RT) on esophageal squamous cell carcinoma (ESCC) and explore the potential mechanisms. ECA109-bearing nude mice were administered RT and/or rh-Endo treatment. Tumor vo...

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Vydáno v:Sci Rep
Hlavní autoři: Zhu, Hongcheng, Yang, Xi, Ding, Yuqiong, Liu, Jia, Lu, Jing, Zhan, Liangliang, Qin, Qin, Zhang, Hao, Chen, Xiaochen, Yang, Yuehua, Yang, Yan, Liu, Zheming, Yang, Meiling, Zhou, Xifa, Cheng, Hongyan, Sun, Xinchen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585975/
https://ncbi.nlm.nih.gov/pubmed/26412785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14503
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