Recombinant human endostatin enhances the radioresponse in esophageal squamous cell carcinoma by normalizing tumor vasculature and reducing hypoxia

The aim of this study was to investigate the effect of recombinant human endostatin (rh-Endo) in combination with radiation therapy (RT) on esophageal squamous cell carcinoma (ESCC) and explore the potential mechanisms. ECA109-bearing nude mice were administered RT and/or rh-Endo treatment. Tumor vo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhu, Hongcheng, Yang, Xi, Ding, Yuqiong, Liu, Jia, Lu, Jing, Zhan, Liangliang, Qin, Qin, Zhang, Hao, Chen, Xiaochen, Yang, Yuehua, Yang, Yan, Liu, Zheming, Yang, Meiling, Zhou, Xifa, Cheng, Hongyan, Sun, Xinchen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585975/
https://ncbi.nlm.nih.gov/pubmed/26412785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14503
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