Coronin7 regulates WASP and SCAR through CRIB mediated interaction with Rac proteins

Coronin7 (CRN7) stabilizes F-actin and is a regulator of processes associated with the actin cytoskeleton. Its loss leads to defects in phagocytosis, motility and development. It harbors a CRIB (Cdc42- and Rac-interactive binding) domain in each of its WD repeat domains which bind to Rac GTPases pre...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Swaminathan, Karthic, Stumpf, Maria, Müller, Rolf, Horn, Anna-Carolin, Schmidbauer, Julia, Eichinger, Ludwig, Müller-Taubenberger, Annette, Faix, Jan, Noegel, Angelika A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585930/
https://ncbi.nlm.nih.gov/pubmed/26411260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14437
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