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A Cdc42- and Rac-interactive binding (CRIB) domain mediates functions of coronin
The Cdc42- and Rac-interactive binding motif (CRIB) of coronin binds to Rho GTPases with a preference for GDP-loaded Rac. Mutation of the Cdc42- and Rac-interactive binding motif abrogates Rac binding. This results in increased 1evels of activated Rac in coronin-deficient Dictyostelium cells (corA(−...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3890859/ https://ncbi.nlm.nih.gov/pubmed/24347642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315368111 |
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