In situ biomarker discovery and label-free molecular histopathological diagnosis of lung cancer by ambient mass spectrometry imaging

Sensitive and spatial exploration of the metabolism of tumors at the metabolome level is highly challenging. In this study, we developed an in situ metabolomics method based on ambient mass spectrometry imaging using air flow-assisted desorption electrospray ionization (AFADESI), which can spatially...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Li, Tiegang, He, Jiuming, Mao, Xinxin, Bi, Ying, Luo, Zhigang, Guo, Chengan, Tang, Fei, Xu, Xin, Wang, Xiaohao, Wang, Mingrong, Chen, Jie, Abliz, Zeper
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585892/
https://ncbi.nlm.nih.gov/pubmed/26404114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14089
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