In situ biomarker discovery and label-free molecular histopathological diagnosis of lung cancer by ambient mass spectrometry imaging

Sensitive and spatial exploration of the metabolism of tumors at the metabolome level is highly challenging. In this study, we developed an in situ metabolomics method based on ambient mass spectrometry imaging using air flow-assisted desorption electrospray ionization (AFADESI), which can spatially...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Li, Tiegang, He, Jiuming, Mao, Xinxin, Bi, Ying, Luo, Zhigang, Guo, Chengan, Tang, Fei, Xu, Xin, Wang, Xiaohao, Wang, Mingrong, Chen, Jie, Abliz, Zeper
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585892/
https://ncbi.nlm.nih.gov/pubmed/26404114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14089
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