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Isoform dependent regulation of human HCN channels by cholesterol

Cholesterol has been shown to regulate numerous ion channels. HCN channels represent the molecular correlate of I(f) or I(h) in sinoatrial node (SAN) and neuronal cells. Previous studies have implicated a role for cholesterol in the regulation of rabbit HCN4 channels with effects on pacing in the ra...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Fürst, Oliver, D’Avanzo, Nazzareno
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585891/
https://ncbi.nlm.nih.gov/pubmed/26404789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14270
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