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Arrhythmogenic effects of mutated L-type Ca(2+)-channels on an optogenetically paced muscular pump in Caenorhabditis elegans

Cardiac arrhythmias are often associated with mutations in ion channels or other proteins. To enable drug development for distinct arrhythmias, model systems are required that allow implementing patient-specific mutations. We assessed a muscular pump in Caenorhabditis elegans. The pharynx utilizes h...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Schüler, Christina, Fischer, Elisabeth, Shaltiel, Lior, Steuer Costa, Wagner, Gottschalk, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585839/
https://ncbi.nlm.nih.gov/pubmed/26399900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14427
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