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Arrhythmogenic effects of mutated L-type Ca(2+)-channels on an optogenetically paced muscular pump in Caenorhabditis elegans
Cardiac arrhythmias are often associated with mutations in ion channels or other proteins. To enable drug development for distinct arrhythmias, model systems are required that allow implementing patient-specific mutations. We assessed a muscular pump in Caenorhabditis elegans. The pharynx utilizes h...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4585839/ https://ncbi.nlm.nih.gov/pubmed/26399900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14427 |
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