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Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs
Myostatin (MSTN) is a dominant inhibitor of skeletal muscle development and growth. Mutations in MSTN gene can lead to muscle hypertrophy or double-muscled (DM) phenotype in cattle, sheep, dog and human. However, there has not been reported significant muscle phenotypes in pigs in association with M...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4585837/ https://ncbi.nlm.nih.gov/pubmed/26400270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14435 |
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