Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs

Myostatin-deficient mice showed a remarkable hypertrophy of skeletal muscle, with a decreased fat mass and enhanced insulin sensitivity. Currently, it is unclear if the inhibition of myostatin could be used as an approach to treat human obesity and insulin resistance. In this study, we investigated...

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Pubblicato in:Oncotarget
Autori principali: Cai, Chunbo, Qian, Lili, Jiang, Shengwang, Sun, Youde, Wang, Qingqing, Ma, Dezun, Xiao, Gaojun, Li, Biao, Xie, Shanshan, Gao, Ting, Chen, Yaoxing, Liu, Jie, An, Xiaorong, Cui, Wentao, Li, Kui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471021/
https://ncbi.nlm.nih.gov/pubmed/28432282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16822
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