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Genome-wide homozygosity signature and risk of Hodgkin lymphoma

Recent studies have reported that regions of homozygosity (ROH) in the genome are detectable in outbred populations and can be associated with an increased risk of malignancy. To examine whether homozygosity is associated with an increased risk of developing Hodgkin lymphoma (HL) we analysed 589 HL...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sud, Amit, Cooke, Rosie, Swerdlow, Anthony J., Houlston, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585760/
https://ncbi.nlm.nih.gov/pubmed/26391888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14315
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