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Edges of human embryonic stem cell colonies display distinct mechanical properties and differentiation potential

In order to understand the mechanisms that guide cell fate decisions during early human development, we closely examined the differentiation process in adherent colonies of human embryonic stem cells (hESCs). Live imaging of the differentiation process reveals that cells on the outer edge of the und...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Rosowski, Kathryn A., Mertz, Aaron F., Norcross, Samuel, Dufresne, Eric R., Horsley, Valerie
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585749/
https://ncbi.nlm.nih.gov/pubmed/26391588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14218
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