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Edges of human embryonic stem cell colonies display distinct mechanical properties and differentiation potential

In order to understand the mechanisms that guide cell fate decisions during early human development, we closely examined the differentiation process in adherent colonies of human embryonic stem cells (hESCs). Live imaging of the differentiation process reveals that cells on the outer edge of the und...

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Publicat a:Sci Rep
Autors principals: Rosowski, Kathryn A., Mertz, Aaron F., Norcross, Samuel, Dufresne, Eric R., Horsley, Valerie
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585749/
https://ncbi.nlm.nih.gov/pubmed/26391588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14218
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