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Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic treatment
Diabetes mellitus is characterized by disrupted glucose homeostasis due to loss or dysfunction of insulin-producing beta cells. In this work, we characterize pancreatic islet development and function in zebrafish mutant for pdx1, a gene which in humans is linked to genetic forms of diabetes and is a...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4585597/ https://ncbi.nlm.nih.gov/pubmed/26384018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14241 |
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