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Endothelin Receptor-A Antagonist Attenuates Retinal Vascular and Neuroretinal Pathology in Diabetic Mice
PURPOSE. We sought to determine the effects of atrasentan, a selective endothelin-A receptor antagonist, on the retinal vascular and structural integrity in a db/db mouse, an animal model of type 2 diabetes and diabetic retinopathy. METHODS. Diabetic mice, 23 weeks old, were given either atrasentan...
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| Published in: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Association for Research in Vision and Ophthalmology
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4585571/ https://ncbi.nlm.nih.gov/pubmed/24644048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13676 |
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