RNase H domain mutations affect the interaction between Moloney murine leukemia virus reverse transcriptase and its primer-template.
The active sites for the polymerase and nuclease activities of Moloney murine leukemia virus (M-MuLV) reverse transcriptase (RT) reside in separate domains of a single polypeptide. We have studied the effects of RNase H domain mutations on DNA polymerase activity. These mutant RTs displayed decrease...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7679498/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1276 |
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