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Daidzin: a potent, selective inhibitor of human mitochondrial aldehyde dehydrogenase.

Human mitochondrial aldehyde dehydrogenase (ALDH-I) is potently, reversibly, and selectively inhibited by an isoflavone isolated from Radix puerariae and identified as daidzin, the 7-glucoside of 4',7-dihydroxyisoflavone. Kinetic analysis with formaldehyde as substrate reveals that daidzin inhi...

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Détails bibliographiques
Auteurs principaux: Keung, W M, Vallee, B L
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC45849/
https://ncbi.nlm.nih.gov/pubmed/8433985
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