Daidzin: a potent, selective inhibitor of human mitochondrial aldehyde dehydrogenase.
Human mitochondrial aldehyde dehydrogenase (ALDH-I) is potently, reversibly, and selectively inhibited by an isoflavone isolated from Radix puerariae and identified as daidzin, the 7-glucoside of 4',7-dihydroxyisoflavone. Kinetic analysis with formaldehyde as substrate reveals that daidzin inhibits...
Spremljeno u:
| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1993
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45849/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8433985/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1247 |
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