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Protective Effect of Triptolide against Glomerular Mesangial Cell Proliferation and Glomerular Fibrosis in Rats Involves the TGF-β1/Smad Signaling Pathway

Triptolide as a main active ingredient of Tripterygium wilfordii is known to be exerting anti-inflammatory, marked immunosuppressive, and podocyte-protective effects. In this study, we investigated the protective effect of triptolide in kidney disease. Rat glomerular mesangial cells were randomly di...

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Библиографические подробности
Опубликовано в: :Evid Based Complement Alternat Med
Главные авторы: Cao, Yingjie, Huang, Xinzhong, Fan, Yaping, Chen, Xiaolan
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584226/
https://ncbi.nlm.nih.gov/pubmed/26451157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/814089
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