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Thrombin-induced microglial activation impairs hippocampal neurogenesis and spatial memory ability in mice
BACKGROUND: To investigate the effects of microglia/macrophages activation induced by intrastriatal thrombin injection on dentate gyrus neurogenesis and spatial memory ability in mice. METHODS: The male C57BL/6 mice were divided into 4 groups of 10: sham, intracerebral hemorrhage (ICH), ICH + hirudi...
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| Publicado no: | Behav Brain Funct |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4584127/ https://ncbi.nlm.nih.gov/pubmed/26410080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12993-015-0075-7 |
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