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Transplantation of mesenchymal stem cells expressing TIMP-1-shRNA improves hepatic fibrosis in CCl(4)-treated rats
This study was to investigate the therapeutic effect of intravenous transplantation of TIMP-1-silencing mesenchymal stem cells (MSCs) in a rat model of liver fibrosis. MSCs were transduced with a lentiviral vector expressing tissue inhibitor of metalloproteinase 1 (TIMP-1)-shRNA, and the liver cirrh...
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| Publicado no: | Int J Clin Exp Pathol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
e-Century Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4583864/ https://ncbi.nlm.nih.gov/pubmed/26464632 |
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