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Host cell heparan sulfate glycosaminoglycans are ligands for OspF-related proteins of the Lyme disease spirochete

Borrelia burgdorferi , the agent of Lyme disease, spreads from the site of the tick bite to tissues such as heart, joints and the nervous system. Host glycosaminoglycans (GAGs), highly modified repeating disaccharides that are present on cell surfaces and in extracellular matrix, are common targets...

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Bibliografske podrobnosti
izdano v:Cell Microbiol
Main Authors: Lin, Yi-Pin, Bhowmick, Rudra, Coburn, Jenifer, Leong, John M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583806/
https://ncbi.nlm.nih.gov/pubmed/25864455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12448
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