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Host cell heparan sulfate glycosaminoglycans are ligands for OspF-related proteins of the Lyme disease spirochete

Borrelia burgdorferi , the agent of Lyme disease, spreads from the site of the tick bite to tissues such as heart, joints and the nervous system. Host glycosaminoglycans (GAGs), highly modified repeating disaccharides that are present on cell surfaces and in extracellular matrix, are common targets...

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Библиографические подробности
Опубликовано в: :Cell Microbiol
Главные авторы: Lin, Yi-Pin, Bhowmick, Rudra, Coburn, Jenifer, Leong, John M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583806/
https://ncbi.nlm.nih.gov/pubmed/25864455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12448
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