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Host cell heparan sulfate glycosaminoglycans are ligands for OspF-related proteins of the Lyme disease spirochete

Borrelia burgdorferi , the agent of Lyme disease, spreads from the site of the tick bite to tissues such as heart, joints and the nervous system. Host glycosaminoglycans (GAGs), highly modified repeating disaccharides that are present on cell surfaces and in extracellular matrix, are common targets...

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Detalhes bibliográficos
Publicado no:Cell Microbiol
Main Authors: Lin, Yi-Pin, Bhowmick, Rudra, Coburn, Jenifer, Leong, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583806/
https://ncbi.nlm.nih.gov/pubmed/25864455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12448
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