Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics.
An approach toward the estimation of binding constants for organic molecules in aqueous solution is presented, based upon a partitioning of the free energy of binding. Consideration is given to polar and hydrophobic contributions and to the entropic cost of rotor restrictions and bimolecular associa...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8433979/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1172 |
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