Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics.

An approach toward the estimation of binding constants for organic molecules in aqueous solution is presented, based upon a partitioning of the free energy of binding. Consideration is given to polar and hydrophobic contributions and to the entropic cost of rotor restrictions and bimolecular associa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Williams, D H, Searle, M S, Mackay, J P, Gerhard, U, Maplestone, R A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC45835/
https://ncbi.nlm.nih.gov/pubmed/8433979
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