HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins

The pathogenesis of peripheral neuropathies in adults is linked to maintenance mechanisms that are not well understood. Here, we elucidate a novel critical maintenance mechanism for Schwann cell (SC)–axon interaction. Using mouse genetics, ablation of the transcriptional regulators histone deacetyla...

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Опубликовано в: :PLoS Biol
Главные авторы: Brügger, Valérie, Engler, Stefanie, Pereira, Jorge A., Ruff, Sophie, Horn, Michael, Welzl, Hans, Münger, Emmanuelle, Vaquié, Adrien, Sidiropoulos, Páris N. M., Egger, Boris, Yotovski, Peter, Filgueira, Luis, Somandin, Christian, Lühmann, Tessa C., D’Antonio, Maurizio, Yamaguchi, Teppei, Matthias, Patrick, Suter, Ueli, Jacob, Claire
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583457/
https://ncbi.nlm.nih.gov/pubmed/26406915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002258
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