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Deletion of the Thrombin Proteolytic Site in Neurofascin 155 Causes Disruption of Nodal and Paranodal Organization

In the central nervous system, myelin is attached to the axon in the paranodal region by a trimolecular complex of Neurofascin155 (NF155) in the myelin membrane, interacting with Caspr1 and Contactin1 on the axolemma. Alternative splicing of a single Neurofascin transcript generates several differen...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Dutta, Dipankar J., Fields, R. Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010152/
https://ncbi.nlm.nih.gov/pubmed/33815060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.576609
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