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Animal models for exploring the pharmacokinetics of breast cancer therapies

INTRODUCTION: Despite massive expenditures in research and development to cure breast cancer, few agents that pass preclinical trials demonstrate efficacy in humans. Although this endeavor relies on murine models to screen for efficacy before progressing to clinical trials, historically there has be...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Metab Toxicol
Main Authors: Rashid, Omar M., Takabe, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583421/
https://ncbi.nlm.nih.gov/pubmed/25416501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2015.983073
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