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Animal models for exploring the pharmacokinetics of breast cancer therapies

INTRODUCTION: Despite massive expenditures in research and development to cure breast cancer, few agents that pass preclinical trials demonstrate efficacy in humans. Although this endeavor relies on murine models to screen for efficacy before progressing to clinical trials, historically there has be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Expert Opin Drug Metab Toxicol
Hauptverfasser: Rashid, Omar M., Takabe, Kazuaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583421/
https://ncbi.nlm.nih.gov/pubmed/25416501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2015.983073
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