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Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil Domain
Rad50 and Mre11 form a complex involved in the detection and processing of DNA double strand breaks. Rad50 contains an anti-parallel coiled-coil with two absolutely conserved cysteine residues at its apex. These cysteine residues serve as a dimerization domain and bind a Zn(2+) cation in a tetrathio...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4583041/ https://ncbi.nlm.nih.gov/pubmed/26242734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675132 |
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