Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil Domain

Rad50 and Mre11 form a complex involved in the detection and processing of DNA double strand breaks. Rad50 contains an anti-parallel coiled-coil with two absolutely conserved cysteine residues at its apex. These cysteine residues serve as a dimerization domain and bind a Zn(2+) cation in a tetrathio...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Barfoot, Tasida, Herdendorf, Timothy J., Behning, Bryanna R., Stohr, Bradley A., Gao, Yang, Kreuzer, Kenneth N., Nelson, Scott W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
DNA and Chromosomes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583041/
https://ncbi.nlm.nih.gov/pubmed/26242734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675132
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