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The Role of the Phylogenetically Conserved Cochaperone Protein Droj2/DNAJA3 in NF-κB Signaling

The NF-κB pathway is a phylogenetically conserved signaling pathway with a central role in inflammatory and immune responses. Here we demonstrate that a cochaperone protein, Droj2/DNAJA3, is involved in the activation of canonical NF-κB signaling in flies and in human cultured cells. Overexpression...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Momiuchi, Yoshiki, Kumada, Kohei, Kuraishi, Takayuki, Takagaki, Takeshi, Aigaki, Toshiro, Oshima, Yoshiteru, Kurata, Shoichiro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583039/
https://ncbi.nlm.nih.gov/pubmed/26245905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.664193
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