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L-type Calcium Channel Ca(v)1.2 Is Required for Maintenance of Auditory Brainstem Nuclei

Ca(v)1.2 and Ca(v)1.3 are the major L-type voltage-gated Ca(2+) channels in the CNS. Yet, their individual in vivo functions are largely unknown. Both channel subunits are expressed in the auditory brainstem, where Ca(v)1.3 is essential for proper maturation. Here, we investigated the role of Ca(v)1...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ebbers, Lena, Satheesh, Somisetty V., Janz, Katrin, Rüttiger, Lukas, Blosa, Maren, Hofmann, Franz, Morawski, Markus, Griesemer, Désirée, Knipper, Marlies, Friauf, Eckhard, Nothwang, Hans Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583033/
https://ncbi.nlm.nih.gov/pubmed/26242732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.672675
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