Immunotherapy with CpG-ODN in neoplastic meningitis: A phase I trial

TLR-9 agonists are immunostimulating agents that have antitumor effects in animal models. A phase I trial was conducted to define the safety profile of subcutaneous injections, combined with intrathecally administration of CpG-28, a TRL 9 agonist, in patients with neoplastic meningitis (NM). Cohorts...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Sci
Main Authors: Ursu, Renata, Taillibert, Sophie, Banissi, Claire, Vicaut, Eric, Bailon, Olivier, Le Rhun, Emilie, Guillamo, Jean-Sebastien, Psimaras, Dimitri, Tibi, Annick, Sacko, Adama, Marantidou, Athina, Belin, Catherine, Carpentier, Antoine F
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582991/
https://ncbi.nlm.nih.gov/pubmed/26094710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12724
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