CD8 T-cell priming upon mRNA vaccination is restricted to bone-marrow-derived antigen-presenting cells and may involve antigen transfer from myocytes

Self-amplifying mRNAs (SAM®) are a novel class of nucleic acid vaccines, delivered by a non-viral delivery system. They are effective at eliciting potent and protective immune responses and are being developed as a platform technology with potential to be used for a broad range of targets. However,...

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Detaylı Bibliyografya
Yayımlandı:Immunology
Asıl Yazarlar: Lazzaro, Sandra, Giovani, Cinzia, Mangiavacchi, Simona, Magini, Diletta, Maione, Domenico, Baudner, Barbara, Geall, Andrew J, De Gregorio, Ennio, D’Oro, Ugo, Buonsanti, Cecilia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Ltd 2015
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582972/
https://ncbi.nlm.nih.gov/pubmed/26173587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12505
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