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A Two-stage Multiplex Method for Quantitative Analysis of Botulinum Neurotoxin type A, B, E, and F by MALDI-TOF Mass Spectrometry

In this publication we report on the development of a quantitative enzymatic method for the detection of four botulinum neurotoxin (BoNT) serotypes responsible for human botulism by MALDI-TOF mass spectrometry. Factors that might affect the linearity and dynamic range for detection of BoNT cleavage...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Anal Chem
Hauptverfasser: Wang, Dongxia, Baudys, Jakub, Krilich, Joan, Smith, Theresa J., Barr, John R., Kalb, Suzanne R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582765/
https://ncbi.nlm.nih.gov/pubmed/25285509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac502948v
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