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Binding of SGTA to Rpn13 selectively modulates protein quality control
Rpn13 is an intrinsic ubiquitin receptor of the 26S proteasome regulatory subunit that facilitates substrate capture prior to degradation. Here we show that the C-terminal region of Rpn13 binds to the tetratricopeptide repeat (TPR) domain of SGTA, a cytosolic factor implicated in the quality control...
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| Veröffentlicht in: | J Cell Sci |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4582187/ https://ncbi.nlm.nih.gov/pubmed/26169395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.165209 |
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