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E4-Ubiquitin ligase Ufd2 stabilizes Yap8 and modulates arsenic stress responses independent of the U-box motif

Adaptation of Saccharomyces cerevisiae cells to arsenic stress is mediated through the activation of arsenic detoxification machinery by the Yap8 transcription factor. Yap8 is targeted by the ubiquitin proteasome system for degradation under physiological conditions, yet it escapes proteolysis in ar...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Ferreira, Rita T., Menezes, Regina A., Rodrigues-Pousada, Claudina
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582114/
https://ncbi.nlm.nih.gov/pubmed/26276098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.010405
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