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Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway

Huntington disease (HD) is a brain disorder characterized by the late onset of motor and cognitive symptoms, even though the neurons in the brain begin to suffer dysfunction and degeneration long before symptoms appear. There is currently no cure. Several molecular and developmental effects of HD ha...

詳細記述

保存先:
書誌詳細
出版年:Dis Model Mech
主要な著者: Szlachcic, Wojciech J., Switonski, Pawel M., Krzyzosiak, Wlodzimierz J., Figlerowicz, Marek, Figiel, Maciej
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582098/
https://ncbi.nlm.nih.gov/pubmed/26092128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.019406
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