Investigating the Robustness and Diagnostic Potential of Extracellular Matrix Remodelling Biomarkers in Alkaptonuria

Background and aim: Alkaptonuria (AKU) clinical manifestations resemble severe arthritis. The Suitability of Nitisinone in Alkaptonuria 1 (SONIA 1) study is a dose-finding trial for nitisinone treatment of AKU patients. We tested a panel of serum and urinary biomarkers reflecting extracellular matri...

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Publicat a:JIMD Rep
Autors principals: Genovese, F., Siebuhr, A. S., Musa, K., Gallagher, J. A., Milan, A. M., Karsdal, M. A., Rovensky, J., Bay-Jensen, A. C., Ranganath, L. R.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582020/
https://ncbi.nlm.nih.gov/pubmed/25786641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2015_430
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