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Defining the effects of storage on platelet bioenergetics; the role of increased proton leak

The quality of platelets decreases over storage time, shortening their shelf life and potentially worsening transfusion outcomes. The changes in mitochondrial function associated with platelet storage are poorly defined and to address this we measured platelet bioenergetics in freshly isolated and s...

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Dettagli Bibliografici
Pubblicato in:Biochim Biophys Acta
Autori principali: Ravi, Saranya, Chacko, Balu, Kramer, Philip A., Sawada, Hirotaka, Johnson, Michelle S., Zhi, Degui, Marques, Marisa B., Darley-Usmar, Victor M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582014/
https://ncbi.nlm.nih.gov/pubmed/26327682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.08.026
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