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Defining the effects of storage on platelet bioenergetics; the role of increased proton leak

The quality of platelets decreases over storage time, shortening their shelf life and potentially worsening transfusion outcomes. The changes in mitochondrial function associated with platelet storage are poorly defined and to address this we measured platelet bioenergetics in freshly isolated and s...

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Vydáno v:Biochim Biophys Acta
Hlavní autoři: Ravi, Saranya, Chacko, Balu, Kramer, Philip A., Sawada, Hirotaka, Johnson, Michelle S., Zhi, Degui, Marques, Marisa B., Darley-Usmar, Victor M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582014/
https://ncbi.nlm.nih.gov/pubmed/26327682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.08.026
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