A KSHV microRNA Directly Targets G Protein-Coupled Receptor Kinase 2 to Promote the Migration and Invasion of Endothelial Cells by Inducing CXCR2 and Activating AKT Signaling

Kaposi's sarcoma (KS) is a highly disseminated angiogenic tumor of endothelial cells linked to infection by Kaposi's sarcoma-associated herpesvirus (KSHV). KSHV encodes more than two dozens of miRNAs but their roles in KSHV-induced tumor dissemination and metastasis remain unknown. Here, w...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Hu, Minmin, Wang, Cong, Li, Wan, Lu, Weiping, Bai, Zhiqiang, Qin, Di, Yan, Qin, Zhu, Jianzhong, Krueger, Brian J., Renne, Rolf, Gao, Shou-Jiang, Lu, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581863/
https://ncbi.nlm.nih.gov/pubmed/26402907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005171
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