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Glycosylation Effects on FSH-FSHR Interaction Dynamics: A Case Study of Different FSH Glycoforms by Molecular Dynamics Simulations

The gonadotropin known as follicle-stimulating hormone (FSH) plays a key role in regulating reproductive processes. Physiologically active FSH is a glycoprotein that can accommodate glycans on up to four asparagine residues, including two sites in the FSHα subunit that are critical for biochemical f...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Meher, Biswa Ranjan, Dixit, Anshuman, Bousfield, George R., Lushington, Gerald H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581761/
https://ncbi.nlm.nih.gov/pubmed/26402790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137897
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