Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing

Precise delineation of the specific genes and pathways altered with aging and estrogen (E) therapy may lead to new skeletal biomarkers and the development of novel bone therapeutics. Previous human bone studies, however, have been limited by only examining pre-specified genes and pathways. High-thro...

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Pubblicato in:PLoS One
Autori principali: Farr, Joshua N., Roforth, Matthew M., Fujita, Koji, Nicks, Kristy M., Cunningham, Julie M., Atkinson, Elizabeth J., Therneau, Terry M., McCready, Louise K., Peterson, James M., Drake, Matthew T., Monroe, David G., Khosla, Sundeep
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581624/
https://ncbi.nlm.nih.gov/pubmed/26402159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138347
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