Global transcriptional profiling using RNA sequencing and DNA methylation patterns in highly enriched mesenchymal cells from young versus elderly women

Age-related bone loss in humans is associated with a decrease in bone formation relative to bone resorption, although the mechanisms for this impairment in bone formation with aging are not well understood. It is known that the precursors for the bone-forming osteoblasts reside in the mesenchymal ce...

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Vydáno v:Bone
Hlavní autoři: Roforth, Matthew M., Farr, Joshua N., Fujita, Koji, McCready, Louise K., Atkinson, Elizabeth J., Therneau, Terry M., Cunningham, Julie M., Drake, Matthew T., Monroe, David G., Khosla, Sundeep
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447531/
https://ncbi.nlm.nih.gov/pubmed/25827254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.03.017
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