Global transcriptional profiling using RNA sequencing and DNA methylation patterns in highly enriched mesenchymal cells from young versus elderly women

Age-related bone loss in humans is associated with a decrease in bone formation relative to bone resorption, although the mechanisms for this impairment in bone formation with aging are not well understood. It is known that the precursors for the bone-forming osteoblasts reside in the mesenchymal ce...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Roforth, Matthew M., Farr, Joshua N., Fujita, Koji, McCready, Louise K., Atkinson, Elizabeth J., Therneau, Terry M., Cunningham, Julie M., Drake, Matthew T., Monroe, David G., Khosla, Sundeep
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447531/
https://ncbi.nlm.nih.gov/pubmed/25827254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.03.017
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