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Effects of the Loss of Conjunctival Muc16 on Corneal Epithelium and Stroma in Mice

PURPOSE. To examine the role of conjunctival Muc16 in the homeostasis of the ocular surface epithelium and stroma using Muc16-null knockout (KO) mice. METHODS. We used KO mice (n = 58) and C57/BL6 (WT) mice (n = 58). Histology and immunohistochemistry were employed to analyze the phenotypes in the o...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Shirai, Kumi, Okada, Yuka, Cheon, Dong-Joo, Miyajima, Masayasu, Behringer, Richard R., Yamanaka, Osamu, Saika, Shizuya
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581617/
https://ncbi.nlm.nih.gov/pubmed/24812549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12955
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