Effects of the Loss of Conjunctival Muc16 on Corneal Epithelium and Stroma in Mice

PURPOSE. To examine the role of conjunctival Muc16 in the homeostasis of the ocular surface epithelium and stroma using Muc16-null knockout (KO) mice. METHODS. We used KO mice (n = 58) and C57/BL6 (WT) mice (n = 58). Histology and immunohistochemistry were employed to analyze the phenotypes in the o...

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Published in:Invest Ophthalmol Vis Sci
Main Authors: Shirai, Kumi, Okada, Yuka, Cheon, Dong-Joo, Miyajima, Masayasu, Behringer, Richard R., Yamanaka, Osamu, Saika, Shizuya
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581617/
https://ncbi.nlm.nih.gov/pubmed/24812549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12955
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